Manage the
Unmanageable CMV
Master the transition from failed Valganciclovir therapy to genotypic-guided rescue. A complete hands-on module for transplant professionals.
Start Simulation play_arrowPhase 01: Sarah's Case
Follow Sarah, a 48-year-old kidney recipient, through a refractory crisis. Your decisions determine graft survival.
Sarah Jenkins
48y Kidney Recipient
Creatinine
1.4 mg/dL
Viral Load
35,000
// CLINICAL NOTE
"Sarah presents with fatigue and leukopenia 1 month post-prophylaxis. Day 14 of therapy."
Therapeutic Failure?
Sarah has been on Valganciclovir 900mg BID for 14 days. Her viral load has only dropped from 38k to 35k IU/mL (< 1 log10 reduction). What is the standard next action?
Interactive Lab 02
The Mutation Landscape
Interact with the 3D virion to identify the two major structural targets of CMV antiviral therapy.
Molecular Diagnosis Bench
Simulate the DNA extraction process to reveal the genotype.
Click the pipette icon to transfer plasma and start extraction.
Viral Kinetics Simulation
Adjust the efficacy of the first-line therapy to model the Breakthrough Rebound. This "U-shaped" curve is a clinical red flag for biological resistance.
Global Mastery Assessment
Complete all 15 questions to claim your credits.